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Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2

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产品编号 TMAC-01499
别名 p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253)

Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FOXO3 (Ser253)。Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 可用于 IF,IHC,WB。

Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2

Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 2

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Rating icon 还可以
产品编号 TMAC-01499 别名 p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253)

Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FOXO3 (Ser253)。Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody 可用于 IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO3 (Ser253). Anti-Phospho-FOXO3 (Ser253) Polyclonal Antibody can be used in IF,IHC,WB.
别名p-FOXO3 (Ser253), p-FOXO3 (S253), FOXO3 (p-Ser253), FOXO3 (p-S253)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from NIH/3T3 cells using FKHRL1 (Ab-253) antibody (Lane 1 and 2) and FKHRL1 (phospho-Ser253) antibody (TMAC-01499, Lane 3 and 4).
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FKHRL1 (phospho-Ser253) antibody (TMAC-01499).
3. Immunofluorescence staining of methanol-fixed HeLa cells using FKHRL1 (phospho-Ser253) antibody (TMAC-01499, Red).
verifiedActivityverifiedActivityverifiedActivity
应用IFIHCWB
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 253(A-V-S(p)-M-D) derived from Human FKHRL1
抗原种属
human
Uniprot ID
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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