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Anti-CD19 Antibody (4E765)
还可以产品编号 TMAY-02134
Anti-CD19 Antibody (4E765) 是一种 Rabbit 抗体，靶向 CD19。Anti-CD19 Antibody (4E765) 可用于 ELISA,IP。
Anti-CD19 Antibody (4E765)
Anti-CD19 Antibody (4E765)
还可以产品编号 TMAY-02134
Anti-CD19 Antibody (4E765) 是一种 Rabbit 抗体，靶向 CD19。Anti-CD19 Antibody (4E765) 可用于 ELISA,IP。
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| 产品描述 | Anti-CD19 Antibody (4E765) is a Rabbit antibody targeting CD19. Anti-CD19 Antibody (4E765) can be used in ELISA,IP. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4E765 |
| 交叉反应 | Human |
| 验证活性 | CD19 was immunoprecipitated using: -Lane A:0.5 mg 293T Whole Cell Lysate. -Lane B:0.5 mg Jurkat Whole Cell Lysate. -Lane C:0.5 mg Daudi Whole Cell Lysate. -2 µL anti-CD19 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-CD19 rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 61 kDa. -Observed band size: 100 kDa |
| 应用 | ELISA,IP |
| 推荐剂量 | ELISA: 1:5000-1:10000; IP: 1-4 μL/mg of lysate |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD19 (rh CD19; TMPY-01949; P15391-1; Met1-Lys291). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CD19 protein (TMPY-01949) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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