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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MLC1 Polyclonal Antibody

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货号 TMAB-08842

Anti-MLC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MLC1。Anti-MLC1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MLC1 Polyclonal Antibody

Anti-MLC1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08842

Anti-MLC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MLC1。Anti-MLC1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-MLC1 Polyclonal Antibody is a Rabbit antibody targeting MLC1. Anti-MLC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein (Potential). Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum.
组织特异性Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景MLC1 is a 377 amino acid multi-pass membrane protein that may serve as a non-selective neuronal cation channel in brain. Mutant MLC1 proteins that show impaired folding have been corrected in vitro with the addition of a Ca(2+)-ATPase inhibitor, curcumin. Mutations in the gene encoding MLC1 is the cause of megalencephalic leukoencephalopathy with subcortical cysts, also known as van der Knaap disease, a rare syndrome characterized early in life by progressive brain destruction causing mental retardation and incoordination. Single nucleotide polymorphisms within the MLC1 gene may be associated with periodic catatonia, but there seems to be conflicting evidence on whether or not the gene is implicated in general schizophrenia.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MLC1
抗原种属
Human
基因名称
MLC1
基因ID
23209
蛋白名称
Membrane protein MLC1
Uniprot ID
Q15049
功能
May be a transporter. May act as a non-selective neuronal cation channel.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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