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Anti-PAK3 Polyclonal Antibody 2

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货号 TMAB-09940

Anti-PAK3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PAK3。Anti-PAK3 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-PAK3 Polyclonal Antibody 2

Anti-PAK3 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-09940

Anti-PAK3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PAK3。Anti-PAK3 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,565
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

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产品描述
Anti-PAK3 Polyclonal Antibody 2 is a Rabbit antibody targeting PAK3. Anti-PAK3 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus
组织特异性Expressed in all adult tissues, with 5-fold lower levels observed in the brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2017]
抗原信息
基因名称
PAK3
基因ID
5063
蛋白名称
Serine/threonine-protein kinase PAK 3
功能
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex
.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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