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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FOX C2 Polyclonal Antibody

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货号 TMAB-06112

Anti-FOX C2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FOX C2。Anti-FOX C2 Polyclonal Antibody 可用于 WB。

Anti-FOX C2 Polyclonal Antibody

Anti-FOX C2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06112

Anti-FOX C2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FOX C2。Anti-FOX C2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-FOX C2 Polyclonal Antibody is a Rabbit antibody targeting FOX C2. Anti-FOX C2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Cow)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FOXC2 is a member of forkhead/winged helix transcription factor family, whose members serve as key regulators in embryogenesis and cell differentiation (3). FOXC2 functions as a key regulator of adipocyte metabolism by increasing the sensitivity of the beta-adrenergic-cAMP-protein kinase A (PKA) signaling pathway through alteration of adipocyte PKA holoenzyme composition (4). Increased FOXC2 levels, induced by high fat diet, seem to counteract most of the symptoms associated with obesity (4). FOXC2 expression is also associated with the early stage of chondrogenic differentiation both in vivo and in vitro (3). FOXC2 haploinsufficiency results in Lymphedema-distichiasis (LD), an autosomal dominant disorder that classically presents as lymphedema of the limbs, and double rows of eyelashes (distichiasis) (5). Mutant mice null for FOXC2 show defects in axial and cranial skeletogenesis, suggesting a requirement of FOXC2 for skeletal tissue development (3). FOXC2 interacts with FOXC1 in the Notch signaling pathway (1) and in kidney and heart development (2).
抗原信息
免疫原
KLH conjugated synthetic peptide: human FOX C2
抗原种属
Human
基因名称
FOXC2
基因ID
2303
蛋白名称
Forkhead box protein C2
Uniprot ID
Q99958
功能
Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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