Bromisoval

Name: Bromisoval
Brand: TargetMol
SKU: T0227
Rating: 4.5 (1 reviews)

一键复制产品信息

很棒

纯度: 98.86%

货号 T0227Cas号 496-67-3

别名 溴米索伐, 溴米那, Isobromyl, Bromovalerylurea, Bromaral, BRN 1773255, 2-Bromo-N-carbamoyl-3-methylbutanamide

Bromisoval (Isobromyl) 具有抗炎活性。

Bromisoval

一键复制产品信息

很棒

纯度: 98.86%

货号 T0227 别名 溴米索伐, 溴米那, Isobromyl, Bromovalerylurea, Bromaral, BRN 1773255, 2-Bromo-N-carbamoyl-3-methylbutanamideCas号 496-67-3

Bromisoval (Isobromyl) 具有抗炎活性。

规格	价格	库存	数量
200 mg	¥ 120	待询
1 mL x 10 mM (in DMSO)	¥ 99	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 98.86%

联系我们获取更多批次信息

资源下载:

COA LCMS HNMR 产品操作手册

产品介绍

Bromisoval AI Summary

Bromisoval shows promising bioactivities across multiple biological targets and pathways. This compound modulates Lamin A splicing, influences Schwann cell PMP22 intronic element activity as demonstrated with firefly luciferase assays, identifies small molecules targeting β-Galactocerebrosidase, and blocks Ebola virus entry in various screening channels. It has been shown to produce potent yet varying effects across different assays, indicating its potential as a multi-target therapeutic. Additionally, in DrugMatrix assays with a daily repeat regimen, Bromisoval has demonstrated significant effects on liver and kidney function, glucose and cholesterol levels, various enzyme and electrolyte levels, as well as detailed blood cell counts and differential cell counts, providing comprehensive insights into its systemic impacts. Furthermore, the compound exhibits moderate antiviral activity against SARS-CoV-2 with an IC50 value above 20,000 nM, showing potential in inhibiting virus-induced cytotoxicity in VERO-6 cells. Interpretation of these results should be conducted by qualified researchers or medical professionals given the complexity and breadth of its bioactive profile..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Bromisoval (Isobromyl) is a mild hypnotic and sedative with potential toxicity.
别名	溴米索伐, 溴米那, Isobromyl, Bromovalerylurea, Bromaral, BRN 1773255, 2-Bromo-N-carbamoyl-3-methylbutanamide

化学信息

分子量	223.07
分子式	C₆H₁₁BrN₂O₂
CAS No.	496-67-3
Smiles	C(C(C(C)C)Br)(NC(N)=O)=O
密度	1.504g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 40 mg/mL (179.32 mM), Sonication is recommended.

Ethanol: Soluble

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (22.41 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4829 mL	22.4145 mL	44.8290 mL	224.1449 mL
5 mM	0.8966 mL	4.4829 mL	8.9658 mL	44.8290 mL
10 mM	0.4483 mL	2.2414 mL	4.4829 mL	22.4145 mL
20 mM	0.2241 mL	1.1207 mL	2.2414 mL	11.2072 mL
50 mM	0.0897 mL	0.4483 mL	0.8966 mL	4.4829 mL
100 mM	0.0448 mL	0.2241 mL	0.4483 mL	2.2414 mL