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Anti-Matriptase Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Matriptase。Anti-Matriptase Polyclonal Antibody 可用于 ICC/IF。
Anti-Matriptase Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Matriptase。Anti-Matriptase Polyclonal Antibody 可用于 ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Matriptase Polyclonal Antibody is a Rabbit antibody targeting Matriptase. Anti-Matriptase Polyclonal Antibody can be used in ICC/IF. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | ICC/IF |
| 推荐剂量 | ICC/IF: 1:50-200 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein (Probable). |
| 组织特异性 | Liver specific. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. |
| 免疫原 | KLH conjugated synthetic peptide: human Matriptase |
| 抗原种属 | Human |
| 基因名称 | TMPRSS6 |
| 基因ID | |
| 蛋白名称 | Transmembrane protease serine 6 |
| Uniprot ID | |
| 功能 | Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Required to sense iron deficiency. Overexpression suppresses activation of the HAMP promoter. |
| 分子量 | Theoretical: 94 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |