生物活性

产品描述	IL-31RA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045249656.2.
生物活性	Immobilized Cynomolgus IL-31RA, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3 ng/ml determined by ELISA (QC Test). Cynomolgus IL-31, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-31 RA, His Tag with an affinity constant of 6.83 nM as determined in SPR assay (Biacore T200).
研究背景	Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMR beta). OSMR beta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs). IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	XP_0452496562
蛋白构建	Ala20-Glu519
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 85% as determined by HPLC
缓冲液	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	58.67 kDa (Predicted); 90-120 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

IL-31RA Protein, Cynomolgus, Recombinant (His)

IL-31RA Protein, Cynomolgus, Recombinant (His)

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