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Anti-Mast Cell Tryptase Antibody (8D176) 是一种 Rabbit 抗体,靶向 Mast Cell Tryptase。Anti-Mast Cell Tryptase Antibody (8D176) 可用于 WB,IHC,IP。
Anti-Mast Cell Tryptase Antibody (8D176) 是一种 Rabbit 抗体,靶向 Mast Cell Tryptase。Anti-Mast Cell Tryptase Antibody (8D176) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-Mast Cell Tryptase Antibody (8D176) is a Rabbit antibody targeting Mast Cell Tryptase. Anti-Mast Cell Tryptase Antibody (8D176) can be used in WB,IHC,IP. |
别名 | Tryptase skin, Tryptase III, tryptase I included, Tryptase I, tryptase beta I included, Tryptase beta 1, tryptase alpha/beta 1, tryptase alpha included, tryptase alpha II included, Tryptase alpha II, tryptase alpha I included, Tryptase alpha 1, Tryptase 1, TPSB1, TPSAB1 protein, TPSAB1, TPS2, TPS1, TPS 1, Skin tryptase, Pituitary tryptase, MCP 7, Mast cell protease II, Mast cell protease 7, Mast cell beta I tryptase, Mast cell alpha II tryptase, Lung tryptase, alpha II |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of Mast Cell Tryptase on human skin lysates using anti-Mast Cell Tryptase antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast cell chymase, known as CMA1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19-amino acid signal peptide, an acidic 2-amino acid propeptide and a 226-amino acid catalytic domain. Tryptases comprise a family of trypsin-like serine proteases that are enzymatically active as heparin-stabilized tetramers. There are four functional genes for tryptase: α I, β I, β II and γ I, which map to human chromosome 16p13.3, with β tryptases representing the main isoenzymes expressed in mast cells. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 30 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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