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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-EBP1 Polyclonal Antibody

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货号 TMAB-05417

Anti-EBP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EBP1。Anti-EBP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-EBP1 Polyclonal Antibody

Anti-EBP1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05417

Anti-EBP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EBP1。Anti-EBP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-EBP1 Polyclonal Antibody is a Rabbit antibody targeting EBP1. Anti-EBP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Pig,Cow,Rabbit,Zebrafish,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus > nucleolus. Tranlocates to the nucleus upon treatment with HRG.
组织特异性Expressed in several cell lines tested, including primary and transformed cell lines.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景EBP1 is a member of the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. It is expressed in a variety of cell lines, including a wide range of tumor cell lines, and localizes to the cytoplasm. Upon treatment with Neuregulin-1 (heregulin), EBP1 translocates to the nucleus. EBP1 is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. In addition, EBP1 interacts with ErbB-3 and may function as a modulator of the ErbB-3-mediated signal transduction pathway by regulating the effects of Neuregulin-1 (heregulin). EBP1 also associates with histone deacetylases (HDACs), functioning as a transcriptional co-repressor of cell cycle regulatory genes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human EBP1
抗原种属
Human
基因名称
PA2G4
基因ID
5036
蛋白名称
Proliferation-associated protein 2G4
Uniprot ID
Q9UQ80
功能
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site).
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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