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Anti-CDCP1 Antibody (1L606)
还可以产品编号 TMAY-03551
Anti-CDCP1 Antibody (1L606) 是一种 Rabbit 抗体，靶向 CDCP1。Anti-CDCP1 Antibody (1L606) 可用于 ELISA。
Anti-CDCP1 Antibody (1L606)
Anti-CDCP1 Antibody (1L606)
还可以产品编号 TMAY-03551
Anti-CDCP1 Antibody (1L606) 是一种 Rabbit 抗体，靶向 CDCP1。Anti-CDCP1 Antibody (1L606) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-CDCP1 Antibody (1L606) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (1L606) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1L606 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CDCP1 (rM CDCP1; TMPY-02901; Q5U462; Met1-Leu666). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migration of ovarian cancer Caov3 and OVCA420 cells with concomitant up-regulation of CDCP1 mRNA and protein. Consistent with a role in cell migration CDCP1 relocates from cell-cell junctions to punctate structures on filopodia after activation of EGFR. It may be involved in cell adhesion and cell matrix association. It also may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. It has been taken as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse CDCP1 Protein (TMPY-02901) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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