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Anti-CASP4 Polyclonal Antibody

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Anti-CASP4 Polyclonal Antibody
产品编号 TMAB-00279

Anti-CASP4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CASP4。Anti-CASP4 Polyclonal Antibody 可用于 WB。

Anti-CASP4 Polyclonal Antibody

Anti-CASP4 Polyclonal Antibody

Rating icon 还可以
Anti-CASP4 Polyclonal Antibody
产品编号 TMAB-00279

Anti-CASP4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CASP4。Anti-CASP4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Rat (predicted:Mouse)
验证活性
Sample:
Lane 1: Rat LympHnode tissue lysates
Lane 2: Rat Lung tissue lysates
Primary: Anti-CASP4 (TMAB-00279) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 10/43 kDa
Observed band size: 47 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
研究背景Caspase 4 is a 377 amino acid protein (43 kDa) that belongs to the Ced3/ICE family of cystein proteases. Caspase 4 is an "upstream" caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have 67% homology to mature Caspase 1 over the equivalent coding sequences. Caspase 4 is capable of cleaving itself and the p30 Caspase 1 precursor, and of inducing apoptosis in transfected insect or COS cells. In high concentrations, it can also cleave the nuclear DNA enzyme PARP but the biological relevance of this cleavage is unclear. Caspase 4 mRNA is found in most tissues examined with the exception of the brain. Highest expression is found in spleen and lung, with moderate expression in heart and liver. Low expression is observed with skeletal muscle, kidney, and testis.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse Caspase-4 subunit p10
抗原种属
Mouse
基因ID
Uniprot ID
研究领域
Caspases
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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