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Anti-CASP4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CASP4。Anti-CASP4 Polyclonal Antibody 可用于 WB。
Anti-CASP4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CASP4。Anti-CASP4 Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Rat (predicted:Mouse) |
验证活性 | Sample: Lane 1: Rat LympHnode tissue lysates Lane 2: Rat Lung tissue lysates Primary: Anti-CASP4 (TMAB-00279) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 10/43 kDa Observed band size: 47 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
研究背景 | Caspase 4 is a 377 amino acid protein (43 kDa) that belongs to the Ced3/ICE family of cystein proteases. Caspase 4 is an "upstream" caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have 67% homology to mature Caspase 1 over the equivalent coding sequences. Caspase 4 is capable of cleaving itself and the p30 Caspase 1 precursor, and of inducing apoptosis in transfected insect or COS cells. In high concentrations, it can also cleave the nuclear DNA enzyme PARP but the biological relevance of this cleavage is unclear. Caspase 4 mRNA is found in most tissues examined with the exception of the brain. Highest expression is found in spleen and lung, with moderate expression in heart and liver. Low expression is observed with skeletal muscle, kidney, and testis. |
免疫原 | KLH conjugated synthetic peptide: mouse Caspase-4 subunit p10 |
抗原种属 | Mouse |
基因ID | |
Uniprot ID | |
研究领域 | Caspases |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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