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Anti-APPL1 Polyclonal Antibody

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货号 TMAB-02785

Anti-APPL1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 APPL1。Anti-APPL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-APPL1 Polyclonal Antibody

Anti-APPL1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02785

Anti-APPL1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 APPL1。Anti-APPL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-APPL1 Polyclonal Antibody is a Rabbit antibody targeting APPL1. Anti-APPL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Early endosome membrane; Peripheral membrane protein. Nucleus. Note=Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
组织特异性High levels in heart, ovary, pancreas and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human APPL1
抗原种属
Human
基因名称
APPL1
基因ID
蛋白名称
DCC-interacting protein 13-alpha
Uniprot ID
功能
Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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