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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MIB1 Antibody (8R298)

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货号 TMAB-08806

Anti-MIB1 Antibody (8R298) 是一种 Rabbit 抗体，靶向 MIB1。Anti-MIB1 Antibody (8R298) 可用于 WB,ICC/IF。

Anti-MIB1 Antibody (8R298)

Anti-MIB1 Antibody (8R298)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08806

Anti-MIB1 Antibody (8R298) 是一种 Rabbit 抗体，靶向 MIB1。Anti-MIB1 Antibody (8R298) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-MIB1 Antibody (8R298) is a Rabbit antibody targeting MIB1. Anti-MIB1 Antibody (8R298) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
8R298
反应种属
Human,Mouse
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Localizes to the plasma membrane (By similarity). According to PubMed:15048887, it is mitochondrial, however such localization remains unclear.
组织特异性Widely expressed at low level. Expressed at higher level in spinal cord, ovary, whole brain, and all specific brain regions examined.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
抗原信息
免疫原
A synthesized peptide: human MIB1
抗原种属
Human
基因名称
MIB1
基因ID
57534
蛋白名称
E3 ubiquitin-protein ligase MIB1
Uniprot ID
Q86YT6
功能
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
化学信息
分子量Theoretical: 110 kDa. Actual: 110 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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