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Anti-Bak Antibody (3J180) 是一种 Rabbit 抗体,靶向 Bak。Anti-Bak Antibody (3J180) 可用于 FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB。
Anti-Bak Antibody (3J180) 是一种 Rabbit 抗体,靶向 Bak。Anti-Bak Antibody (3J180) 可用于 FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-Bak Antibody (3J180) is a Rabbit antibody targeting Bak. Anti-Bak Antibody (3J180) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| 克隆号 | 3J180 |
| 反应种属 | Human |
| 应用 | FCMICC/IFIFIHC-FrIHC-PIPWB |
| 推荐剂量 | FCM=1 μg/Test; ICC/IF=1:100-500; IF=1:200-500; IHC-Fr=1:200-500; IHC-P=1:200-500; IP=1:20-50; WB=1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion membrane. |
| 组织特异性 | Expressed in a wide variety of tissues. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. |
| 免疫原 | A synthesized peptide: human BAK1 |
| 抗原种属 | Human |
| 基因名称 | BAK1 |
| 基因ID | |
| 蛋白名称 | Bcl-2 homologous antagonist/killer |
| Uniprot ID | |
| 功能 | In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. |
| 分子量 | Theoretical: 23 kDa. Actual: 23 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |