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Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603)
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产品编号 TMAB-01660
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) 是一种 Mouse 抗体，靶向 SARS-CoV-2 (2019-nCoV) Spike Neutralizing。Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) 可用于 ELISA。
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603)
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603)
还可以产品编号 TMAB-01660
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) 是一种 Mouse 抗体，靶向 SARS-CoV-2 (2019-nCoV) Spike Neutralizing。Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 3,585 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) is a Mouse antibody targeting SARS-CoV-2 (2019-nCoV) Spike Neutralizing. Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) can be used in ELISA. |
| Ig Type | IgG1 |
| 克隆号 | 7D603 |
| 交叉反应 | Virus |
| 验证活性 | 1. The ACE2-coated plate is incubated with SARS-CoV-2 Spike RBD-HRP (WT) and Anti-SARS-CoV-2 Spike RBD Neutralizing antibody. Percent inhibition is calculated based on the OD value by inhibiting RBD: ACE2 interaction. 2. Direct ELISA was used to detect the binding ability of anti-RBD monoclonal antibody to RBD domain proteins of different SARS-CoV-2 Mutant Strains. Immobilized SARS-CoV-2 RBD proteins, at 2 μg/ml (100ul/Well) can bind Anti-RBD monoclonal antibody-HRP at 1 μg/ml (100ul/Well). |
| 应用 | |
| 推荐剂量 | ELISA: 1:5000-10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Virion membrane ; Single-pass type I membrane protein ; Host endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type I membrane protein ; Host cell membrane ; Single-pass type I membrane protein ;Note: Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Colocalizes with S in the host endoplasmic reticulum-Golgi intermediate compartment. Some S oligomers are transported to the host plasma membrane, where they may mediate cell-cell fusion. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M PBS (pH7.4). |
| 研究背景 | The SARS-CoV-2 spike (S) protein is the target of vaccine design efforts to end the COVID-19 pandemic. Despite a low mutation rate, isolates with the D614G substitution in the S protein appeared early during the pandemic, and are now the dominant form worldwide. Here, we analyze the D614G mutation in the context of a soluble S ectodomain construct. |
| 免疫原 | Recombinant Protein: SARS-CoV-2 Spike S1 Protein |
| 研究领域 | SARS Coronavirus |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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