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HMGCR Protein, Human, Recombinant (His)

Synonyms: HMGCR, HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase
货号 TMPH-00007 一键复制产品信息
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Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.

HMGCR Protein, Human, Recombinant (His)

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货号 TMPH-00007

别名 HMGCR, HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.

HMGCR Protein, Human, Recombinant (His)
其他形式的 “HMGCR Protein, Human, Recombinant (His)”:
HMGCR Protein, Mouse, Recombinant (His)TMPH-02476
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规格价格库存数量
5 μg
¥ 489
3日内发货
10 μg
¥ 797
3日内发货
20 μg
¥ 1,320
现货
50 μg
¥ 1,970
3日内发货
100 μg
¥ 2,680
现货
200 μg
¥ 4,160
20日内发货
500 μg
¥ 7,490
20日内发货
1 mg
¥ 12,200
20日内发货
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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
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选择批次:
纯度: > 90 % as determined by SDS-PAGE
颜色: 白色
性状: Lyophilized powder
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
种属
Human
表达系统
E. coli
标签N-6xHis
蛋白编号P04035
氨基酸序列MTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKT
蛋白构建588-887 aa
蛋白纯度
> 90% as determined by SDS-PAGE.
HMGCR Protein, Human, Recombinant (His)
缓冲液Tris-based buffer, 50% glycerol
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名HMGCR, HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量36.0 kDa (predicted)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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