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Anti-AKR1B1 Antibody (4W828)
还可以产品编号 TMAY-01831
别名 MGC1804, AR, ALR2, ALDR1, aldo-keto reductase family 1, member B1 (aldose reductase), ADR
Anti-AKR1B1 Antibody (4W828) 是一种 Rabbit 抗体，靶向 AKR1B1。Anti-AKR1B1 Antibody (4W828) 可用于 FCM。
Anti-AKR1B1 Antibody (4W828)
Anti-AKR1B1 Antibody (4W828)
还可以产品编号 TMAY-01831 别名 MGC1804, AR, ALR2, ALDR1, aldo-keto reductase family 1, member B1 (aldose reductase), ADR
Anti-AKR1B1 Antibody (4W828) 是一种 Rabbit 抗体，靶向 AKR1B1。Anti-AKR1B1 Antibody (4W828) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-AKR1B1 Antibody (4W828) is a Rabbit antibody targeting AKR1B1. Anti-AKR1B1 Antibody (4W828) can be used in FCM. |
| 别名 | MGC1804, AR, ALR2, ALDR1, aldo-keto reductase family 1, member B1 (aldose reductase), ADR |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4W828 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human AKR1B1 expression on HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human AKR1B1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human AKR1B1 (rh AKR1B1; TMPY-02438; P15121; Met1-Phe316). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the collecting tubule cells and thought to provide protection against hypertonic environment. Some human tissues contain AKR1B1 as well as AKR1B10, a closely related member of the aldo-keto reductase superfamily. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human AKR1B1 Protein (TMPY-02438) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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