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Anti-DYNLL1 Antibody (5G489)

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Anti-DYNLL1 Antibody (5G489)
产品编号 TMAC-01200
别名 Protein Inhibitor of Neuronal Nitric Oxide Synthase, PIN, HDLC1, DYNLL1, Dynein Light Chain LC8-Type 1, Dynein Light Chain 1 Cytoplasmic, DNCLC1, DNCL1, DLC8, DLC1, 8 kDa Dynein Light Chain

Anti-DYNLL1 Antibody (5G489) 是一种 Rabbit 抗体,靶向 DYNLL1。Anti-DYNLL1 Antibody (5G489) 可用于 WB,ICC/IF,IHC,IP。

Anti-DYNLL1 Antibody (5G489)

Anti-DYNLL1 Antibody (5G489)

Rating icon 还可以
Anti-DYNLL1 Antibody (5G489)
产品编号 TMAC-01200 别名 Protein Inhibitor of Neuronal Nitric Oxide Synthase, PIN, HDLC1, DYNLL1, Dynein Light Chain LC8-Type 1, Dynein Light Chain 1 Cytoplasmic, DNCLC1, DNCL1, DLC8, DLC1, 8 kDa Dynein Light Chain

Anti-DYNLL1 Antibody (5G489) 是一种 Rabbit 抗体,靶向 DYNLL1。Anti-DYNLL1 Antibody (5G489) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-DYNLL1 Antibody (5G489) is a Rabbit antibody targeting DYNLL1. Anti-DYNLL1 Antibody (5G489) can be used in WB,ICC/IF,IHC,IP.
别名Protein Inhibitor of Neuronal Nitric Oxide Synthase, PIN, HDLC1, DYNLL1, Dynein Light Chain LC8-Type 1, Dynein Light Chain 1 Cytoplasmic, DNCLC1, DNCL1, DLC8, DLC1, 8 kDa Dynein Light Chain
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of DYNLL1 on MCF-7 cells lysates using anti-DYNLL1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-DYNLL1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded rat esophagus tissue using anti-DYNLL1 antibody. Counter stained with hematoxylin.
4. ICC staining DYNLL1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining DYNLL1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining DYNLL1 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. The highly conserved DYNLL proteins were originally identified as light chains for microtubule-based motor protein Dynein. In mammals there are two closely related isoforms expressed, DYNLL1 and DYNLL2 which share 93% sequence identity at the protein level. DYNLL1 (Dynein light chain 1) also designated, DLC8 or PIN (Protein inhibitor of neuronal nitric oxide synthase) has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Dimerization is required for NOS1 activity and DYNLL1 has been shown to destabilize the NOS1 dimer. Nitric oxide may be involved in several processes such as apoptosis, synaptogenesis and neuronal development; thus DYNLL1 is implicated in these processes as well. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 10 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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