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Cadherin 17/CDH17 Protein, Human, Recombinant (Active, His)
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货号 TMPJ-00583
别名 Liver-Intestine Cadherin, LI-Cadherin, Intestinal Peptide-Associated Transporter HPT-1, CDH17, Cadherin-17
Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.
其他形式的 “Cadherin 17/CDH17 Protein, Human, Recombinant (Active, His)”:
Cadherin 17/CDH17 Protein, Human, Recombinant (Active, His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPJ-00583 别名 Liver-Intestine Cadherin, LI-Cadherin, Intestinal Peptide-Associated Transporter HPT-1, CDH17, Cadherin-17
Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 693 | 6-8日内发货 | |
| 10 μg | ¥ 1,170 | 6-8日内发货 | |
| 20 μg | ¥ 1,860 | 5日内发货 | |
| 50 μg | ¥ 3,470 | 5日内发货 | |
| 100 μg | ¥ 4,930 | 5日内发货 | |
| 200 μg | ¥ 7,350 | 5日内发货 | |
| 500 μg | ¥ 12,100 | 5日内发货 | |
| 1 mg | ¥ 17,300 | 5日内发货 |
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| 产品描述 | Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport. |
| 生物活性 | 1. Immobilized CDH17 Protein, Human, Recombinant (His) at 2 μg/mL (100 μL/well) can bind Anti-Human Cadherin-17 mab (Human IgG1). The ED50 of Anti-Human Cadherin-17 mab (Human IgG1) is 7.34 ng/mL. (Regularly tested). 2. Loaded Anti-Human Cadherin-17 mab (Human IgG1) on Pro-A Biosensor, can bind CDH17 Protein, Human, Recombinant (His) with an affinity constant of 0.827 uM as determined in BLI assay. (Regularly tested) |
| 研究背景 | Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-6xHis |
| 蛋白编号 | AAI13465.1 |
| 氨基酸序列 | Gln23-Met787 |
| 蛋白构建 | Gln23-Met787 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC. |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | Liver-Intestine Cadherin, LI-Cadherin, Intestinal Peptide-Associated Transporter HPT-1, CDH17, Cadherin-17 |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 110-130 KDa (reducing condition) |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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