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Anti-PDE2A Antibody (3F805)
还可以产品编号 TMAH-00867
别名 phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE
Anti-PDE2A Antibody (3F805) 是一种抗体，靶向 PDE2A。Anti-PDE2A Antibody (3F805) 可用于 ELISA, IF。
Anti-PDE2A Antibody (3F805)
Anti-PDE2A Antibody (3F805)
还可以产品编号 TMAH-00867 别名 phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE
Anti-PDE2A Antibody (3F805) 是一种抗体，靶向 PDE2A。Anti-PDE2A Antibody (3F805) 可用于 ELISA, IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-PDE2A Antibody (3F805) is an antibody targeting PDE2A. Anti-PDE2A Antibody (3F805) can be used in ELISA, IF. |
| 别名 | phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE |
| Ig Type | Rabbit IgG |
| 克隆号 | 3F805 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of HepG2 cell with TMAH-00867 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 569-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| 应用 | ELISA, IF |
| 推荐剂量 | IF:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | [Isoform PDE2A3]: Cell membrane; Lipid-anchor.; [Isoform PDE2A2]: Mitochondrion matrix. Mitochondrion inner membrane. Mitochondrion outer membrane.; [Isoform PDE2A1]: Cytoplasm.; [Isoform 5]: Mitochondrion. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line). Regulates mitochondrial cAMP levels and respiration. Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human PDE2A |
| 抗原种属 | Human |
| 基因ID | 5138 |
| Uniprot ID | |
| 研究领域 | Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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