[D-Trp11]-Neurotensin

Name: [D-Trp11]-Neurotensin
Brand: TargetMol
SKU: T40850
Rating: 4.5 (1 reviews)

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产品编号 T40850Cas号 73634-68-1

别名 [D-Trp11]-Neurotensin

[D-Trp11]-Neurotensin is a compound that functions as a selective antagonist of Neurotensin (NT) in perfused rat hearts, while exhibiting full agonist properties in guinea pig atria and rat stomach strips. Additionally, this compound can inhibit hypotension induced by NT.

[D-Trp11]-Neurotensin

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产品编号 T40850 别名 [D-Trp11]-NeurotensinCas号 73634-68-1

规格	价格	库存	数量
25 mg	¥ 10,600	6-8周

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生物活性

产品描述	[D-Trp11]-Neurotensin is a compound that functions as a selective antagonist of Neurotensin (NT) in perfused rat hearts, while exhibiting full agonist properties in guinea pig atria and rat stomach strips. Additionally, this compound can inhibit hypotension induced by NT.
体外活性	[D-Trp11]-Neurotensin (0.13-1.1 μM) markedly inhibits NT-induced coronary vessel constriction in perfused rat hearts[1]. [D-Trp11]-Neurotensin (2-110 μM) exhibits NT-like activity in perfused rat hearts[1].
体内活性	[D-Trp11]-Neurotensin (50-500 nmol/kg; i.v.) has hypotensive activity in pentobarbital-anesthetized rats, with an ED 25 of 122 nmol/kg[2].
别名	[D-Trp11]-Neurotensin

化学信息

分子量	1695.991
分子式	C₈₀H₁₂₂N₂₂O₁₉
CAS No.	73634-68-1
密度	no data available
Sequence	{Pyr}-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-{D-Trp}-Ile-Leu
Sequence Short	{Pyr}-LYENKPRRP-{D-Trp}-IL