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Anti-AU5 tag Polyclonal Antibody

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货号 TMAB-02970

Anti-AU5 tag Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AU5 tag。Anti-AU5 tag Polyclonal Antibody 可用于 WB,ELISA。

Anti-AU5 tag Polyclonal Antibody

Anti-AU5 tag Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02970

Anti-AU5 tag Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AU5 tag。Anti-AU5 tag Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
100 μL
¥ 960
5日内发货
500 μL
¥ 3,990
5日内发货
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产品介绍

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产品描述
Anti-AU5 tag Polyclonal Antibody is a Rabbit antibody targeting AU5 tag. Anti-AU5 tag Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Species independent
应用WBELISA
推荐剂量
WB: 1:1000-5000; ELISA: 1:1000-5000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
抗原信息
免疫原
KLH conjugated AU5 tag
蛋白名称
AU5 tag
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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