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Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2

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产品编号 TMAB-10986

Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-MEK2 (Thr394)。Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2

Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10986

Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-MEK2 (Thr394)。Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,970
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200 μL
¥ 2,795
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产品介绍

生物活性
产品描述
Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-MEK2 (Thr394). Anti-Phospho-MEK2 (Thr394) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Mouse,Rat (predicted:Human)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole body. Cytoplasm. Nucleus. Note=Localizes at centrosomes during prometaphase, midzone during anaphase and midbody during telophase/cytokinesis.
组织特异性Widely expressed, with extremely low levels in brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human MEK2 around the phosphorylation site of Thr394
抗原种属
Human
基因名称
MAP2K2
基因ID
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 2
Uniprot ID
功能
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases.
化学信息
分子量Theoretical: 46 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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