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顶部生物活性储存和溶解信息计算器

Anti-VE-Cadherin Antibody (3L899)

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产品编号 TMAY-03800

别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody (3L899) 是一种 Mouse 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody (3L899) 可用于 WB。

Anti-VE-Cadherin Antibody (3L899)

Anti-VE-Cadherin Antibody (3L899)

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Rating icon 还可以
产品编号 TMAY-03800 别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody (3L899) 是一种 Mouse 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody (3L899) 可用于 WB。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-VE-Cadherin Antibody (3L899) is a Mouse antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (3L899) can be used in WB.
别名cadherin 5, type 2 (vascular endothelium)
Ig Type
Mouse IgG2a
克隆号
3L899
交叉反应
Rat
特异性
Rat VE-Cadherin
验证活性
Anti-CDH5 mouse monoclonal antibody at 1:500 dilution.
-Lane A: A549 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:88 kDa.
-Observed band size:78 kDa
应用WB
推荐剂量
WB: 1:500-1:1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat VE-Cadherin / CD144 / CDH5 (rR VE-Cadherin / CD144 / CDH5; TMPY-03305; NP_001100877.1; Met1-Gln585). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat VE-Cadherin / CD144 / CDH5 protein (TMPY-03305)
抗原种属
Rat
研究领域
Hemangioblast Markers, Cardiac Stem Cell Markers
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

vascular endotheliumcadherin 5, type 2

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