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Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3

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产品编号 TMAB-10776

Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-HDAC7 (Ser155)。Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3

Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10776

Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-HDAC7 (Ser155)。Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3 is a Rabbit antibody targeting Phospho-HDAC7 (Ser155). Anti-Phospho-HDAC7 (Ser155) Polyclonal Antibody 3 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Human,Mouse (predicted:Rat,Chicken,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Note=In the nucleus, it associates with distinct subnuclear dot-like structures. Shuttles between the nucleus and the cytoplasm. Treatment with EDN1 results in shuttling from the nucleus to the perinuclear region. The export to cytoplasm depends on the interaction with the 14-3-3 protein YWHAE and is due to its phosphorylation.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human HDAC7 around the phosphorylation site of Ser155
抗原种属
Human
基因名称
HDAC7
基因ID
51564
蛋白名称
Histone deacetylase 7
Uniprot ID
Q8WUI4
功能
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.
化学信息
分子量Theoretical: 119 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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