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Anti-ENT1 Polyclonal Antibody

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货号 TMAB-05593

Anti-ENT1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ENT1。Anti-ENT1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ENT1 Polyclonal Antibody

Anti-ENT1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05593

Anti-ENT1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ENT1。Anti-ENT1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ENT1 Polyclonal Antibody is a Rabbit antibody targeting ENT1. Anti-ENT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Cow,Horse,Sheep, Cynomolgus Monkey, Orangutan)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Basolateral cell membrane. Apical cell membrane. Predominantly localized in the basolateral membrane in polarised MDCK cells.
组织特异性Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ENT1/SLC29A1
抗原种属
Human
基因名称
SLC29A1
基因ID
2030
蛋白名称
Equilibrative nucleoside transporter 1
Uniprot ID
Q99808
功能
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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