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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Sphingomyelin Synthase 2 Polyclonal Antibody

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货号 TMAB-13109

Anti-Sphingomyelin Synthase 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Sphingomyelin Synthase 2。Anti-Sphingomyelin Synthase 2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Sphingomyelin Synthase 2 Polyclonal Antibody

Anti-Sphingomyelin Synthase 2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13109

Anti-Sphingomyelin Synthase 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Sphingomyelin Synthase 2。Anti-Sphingomyelin Synthase 2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Sphingomyelin Synthase 2 Polyclonal Antibody is a Rabbit antibody targeting Sphingomyelin Synthase 2. Anti-Sphingomyelin Synthase 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly plasma membrane, some in Golgi apparatus. Some localization in the perinuclear region where it colocalizes with a sialyltransferase.
组织特异性Brain, heart, kidney, liver, muscle and stomach. Also expressed in a number of cell lines such as carcinoma HeLa cells, hepatoma Hep-G2 cells, and colon carcinoma Caco-2 cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined.[provided by RefSeq, Oct 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Sphingomyelin Synthase 2
抗原种属
Human
基因名称
SGMS2
基因ID
166929
蛋白名称
Phosphatidylcholine:ceramide cholinephosphotransferase 2
Uniprot ID
Q8NHU3
功能
Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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