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Anti-SOX-2 Antibody (2A191)

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货号 TMAY-00057

Anti-SOX-2 Antibody (2A191) 是一种 Rabbit 抗体,靶向 SOX-2。Anti-SOX-2 Antibody (2A191) 可用于 WB。

Anti-SOX-2 Antibody (2A191)

Anti-SOX-2 Antibody (2A191)

一键复制产品信息
Rating icon 还可以
货号 TMAY-00057

Anti-SOX-2 Antibody (2A191) 是一种 Rabbit 抗体,靶向 SOX-2。Anti-SOX-2 Antibody (2A191) 可用于 WB。

规格价格库存数量
100 μL
¥ 2,294
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产品介绍


生物活性
产品描述
Anti-SOX-2 Antibody (2A191) is a Rabbit antibody targeting SOX-2. Anti-SOX-2 Antibody (2A191) can be used in WB.
Ig Type
Rabbit IgG
克隆号
2A191
反应种属
Human
特异性
Human SOX2
验证活性
Anti-Sox2 rabbit monoclonal antibody at 1:500 dilution.
-Lane A: hESC-H9 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:34 kDa.
-Observed band size:37 kDa
应用WB
推荐剂量
WB: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the human Sox2.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SOX2 is a member of the SOXB1 subfamily of transcription factors most notably involved in the reprogramming of somatic cells into induced pluripotent stem cells. Housed on chromosome 3, the SOX2 gene encodes for a protein with a C-terminal transcriptional activation domain and a DNA-binding HMG domain that contains a nuclear localization/export signal. SOX2 forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development and pluripotency such as YES1, FGF4, UTF1 and ZFP206. Mutations in this gene have been associated with bilateral eye disease. SOX2 antigen and antibody were found in small-cell lung cancer cell lines and sera. However, neither exists in normal sera, suggesting that SOX2 might be a potential tumor target or marker.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: N-terminus of the human Sox2.
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

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