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C-MPL Protein, Cynomolgus, Recombinant (His)

C-MPL Protein, Cynomolgus, Recombinant (His)

产品编号 TMPK-00494
别名: TPO-R, MPLV, K12, CD110, MPL, c-Mpl

C-MPL Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.48 kDa and the accession number is A0A2K5UGC7.

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C-MPL Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,100 5日内发货
500 μg ¥ 12,400 5日内发货
1 mg ¥ 20,700 5日内发货
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产品目录号及名称: C-MPL Protein, Cynomolgus, Recombinant (His) (TMPK-00494)
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生物活性
技术参数
产品性质
参考文献
生物活性 Immobilized Cynomolgus c-MPL, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA.
产品描述 C-MPL Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.48 kDa and the accession number is A0A2K5UGC7.
种属 Cynomolgus
表达系统 HEK293 Cells
标签 C-His
蛋白编号 A0A2K5UGC7
别名 TPO-R, MPLV, K12, CD110, MPL, c-Mpl
蛋白构建 Gln22-Thr489
蛋白纯度 > 95% as determined by Tris-Bis PAGE
分子量 53.48 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 3 mM DTT, 10% Glycerol (pH 7.5).
存储

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.

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Keywords

C-MPL Protein, Cynomolgus, Recombinant (His) K 12 TPO-R K-12 MPLV K12 CD110 CD-110 MPL c-Mpl CD 110 recombinant recombinant-proteins proteins protein

 

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