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Anti-ATP1B4 Antibody (4E867)
还可以产品编号 TMAY-02439
Anti-ATP1B4 Antibody (4E867) 是一种 Mouse 抗体，靶向 ATP1B4。Anti-ATP1B4 Antibody (4E867) 可用于 ELISA。
Anti-ATP1B4 Antibody (4E867)
Anti-ATP1B4 Antibody (4E867)
还可以产品编号 TMAY-02439
Anti-ATP1B4 Antibody (4E867) 是一种 Mouse 抗体，靶向 ATP1B4。Anti-ATP1B4 Antibody (4E867) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-ATP1B4 Antibody (4E867) is a Mouse antibody targeting ATP1B4. Anti-ATP1B4 Antibody (4E867) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 4E867 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ATP1B4 (mature form, NP_036201.1; Tyr 132-Thr 357). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | ATP1B4 is a member of the X(+)/potassium ATPases subunit beta family. It is highly expressed in skeletal muscle and at a lower level in heart. ATP1B4 gene can be found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na, K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. ATP1B4 may act as a transcriptional coregulator during muscle development through its interaction with SNW1. Na+, K+-ATPase is an important regulator of intracellular electrolyte levels in most mammalian cells. It is a Mg2+-dependent transport pump responsible for maintaining the low intracellular Na+:K+ ratio that is essential for cell homeostasis and physiological function. It catalyzes the active uptake of K+ and extrusion of Na+ at the expense of hydrolyzing ATP with a stoichiometry of 3 Na+ for 2 K+. ATP1B4 has lost its ancestral function as a Na,K-ATPase beta-subunit. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human ATP1B4 protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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