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Anti-OX40/TNFRSF4 Antibody (2E203)
还可以产品编号 TMAY-00885
Anti-OX40/TNFRSF4 Antibody (2E203) 是一种 Mouse 抗体，靶向 OX40/TNFRSF4。Anti-OX40/TNFRSF4 Antibody (2E203) 可用于 FCM。
Anti-OX40/TNFRSF4 Antibody (2E203)
Anti-OX40/TNFRSF4 Antibody (2E203)
还可以产品编号 TMAY-00885
Anti-OX40/TNFRSF4 Antibody (2E203) 是一种 Mouse 抗体，靶向 OX40/TNFRSF4。Anti-OX40/TNFRSF4 Antibody (2E203) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-OX40/TNFRSF4 Antibody (2E203) is a Mouse antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody (2E203) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2E203 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human OX40 expression on PHA-activated human whole blood lymphocytes. Cells were stained with purified anti-Human OX40, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | FITC/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human OX40 Protein (TMPY-01423) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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