Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
规格 | 价格/CNY | 货期 | 数量 | |
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50 μg | ¥ 3,320 | 现货 | ||
100 μg | ¥ 5,180 | 5日内发货 | ||
200 μg | ¥ 8,060 | 5日内发货 | ||
500 μg | ¥ 14,450 | 5日内发货 |
生物活性 |
Immobilized Human Fas/CD95 hFc at 2 μg/mL (100 μL/well) can bind Human Fas Ligand His , the EC50 of Human Fas Ligand His is 40-200 ng/mL.
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产品描述 | Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
种属 | Human |
表达系统 | Yeast |
标签 | His |
蛋白编号 | P48023-1 |
别名 | TNLG1A, FASL, FASLG, CD178, CD95-L, APT1LG1, APTL, CD95L, Fas ligand, ALPS1B, TNFSF6 |
蛋白构建 | A DNA sequence encoding human FASLG (NP_000630.1) (Pro134-Leu281) was expressed with a polyhistidine tag at the N-terminus. |
蛋白纯度 |
> 90 % as determined by SDS-PAGE
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分子量 | Approxiamtely 19.3 kDa |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
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Fas Ligand Protein, Human, Recombinant (His) TNFSF-6 TNLG1A CD 178 FASL FASLG CD178 CD95-L APT1LG1 APTL CD-178 CD95L Fas ligand ALPS1B TNFSF 6 TNFSF6 recombinant recombinant-proteins proteins protein