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Fas Ligand Protein, Human, Recombinant (His)

产品编号 TMPY-03956

Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 19.3 kDa and the accession number is P48023-1.

Fas Ligand Protein, Human, Recombinant (His)

产品编号 TMPY-03956

规格	价格	库存
50 μg	¥ 3,320	In stock
100 μg	¥ 5,180	5日内发货
200 μg	¥ 8,060	5日内发货
500 μg	¥ 14,450	5日内发货

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产品信息

生物活性	Immobilized Human Fas/CD95 hFc at 2 μg/mL (100 μL/well) can bind Human Fas Ligand His , the EC50 of Human Fas Ligand His is 40-200 ng/mL.
产品描述	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 19.3 kDa and the accession number is P48023-1.
种属	Human
表达系统	P. pastoris (Yeast)
标签	N-His
蛋白编号	P48023-1
别名	TNLG1A,TNFSF6,FASLG,FASL,Fas ligand,CD95-L,CD95L,CD178,APTL,APT1LG1,ALPS1B
蛋白构建	A DNA sequence encoding human FASLG (NP_000630.1) (Pro134-Leu281) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
蛋白纯度	> 90 % as determined by SDS-PAGE
分子量	19.3 kDa (predicted); 26 kDa (reducing conditions)
内毒素	Please contact us for more information.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.