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Anti-ATPIF1 Polyclonal Antibody

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货号 TMAB-02959

Anti-ATPIF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ATPIF1。Anti-ATPIF1 Polyclonal Antibody 可用于 WB。

Anti-ATPIF1 Polyclonal Antibody

Anti-ATPIF1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02959

Anti-ATPIF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ATPIF1。Anti-ATPIF1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-ATPIF1 Polyclonal Antibody is a Rabbit antibody targeting ATPIF1. Anti-ATPIF1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Mitochondrial ATP synthases (ATPases) transduce the energy contained in membrane electrochemical proton gradients into the energy required for synthesis of high-energy phosphate bonds. ATPases contain two linked complexes: F1, the hydrophilic catalytic core; and F0, the membrane-embedded protein channel. F1 consists of three Alpha chains and three Beta chains, which are weakly homologous, as well as one Gamma chain, one Delta chain and one Gamma chain. F0 consists of three subunits: a, b and c. A mitochondrial F1-ATPase inhibitor protein, ATPIF1 (ATPase inhibitory factor 1), also known as IP, IF1, ATPI or ATPIP (ATPase inhibitor protein), binds to the C-terminal region of a Beta subunit of the F1-ATPase at low pH values and, via interference of the Beta and Gamma subunit interaction, ATPIF1 regulates the activity of the F1F0-ATPase. This reversible ATPIF1 binding to F1F0-ATPase also occurs on the surface of endothelial cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ATPIF1/ATPase Inhibitory Factor 1
抗原种属
Human
基因名称
ATP5IF1
基因ID
蛋白名称
ATPase inhibitor, mitochondrial
Uniprot ID
功能
Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix.
化学信息
分子量Theoretical: 10 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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