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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-C1s Polyclonal Antibody

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货号 TMAB-03368

Anti-C1s Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C1s。Anti-C1s Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-C1s Polyclonal Antibody

Anti-C1s Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03368

Anti-C1s Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C1s。Anti-C1s Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-C1s Polyclonal Antibody is a Rabbit antibody targeting C1s. Anti-C1s Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Horse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The complement component proteins, C1, C3, C4, and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation, and cellular chemotaxis. C1q, together with proenzymes C1r and C1s, yield C1, the first component of the classical pathway of the serum complement system. C1 consists of a calcium dependent trimolecular complex of C1r, C1s and C1q in a 2:2:1 ratio. Activated C1s is in the form of a disulfide-linked heterodimer consisting of a heavy chain and a light chain. Defects in the gene encoding for C1s can cause selective C1s deficiency, a disorder characterized by early onset of various autoimmune diseases.
抗原信息
免疫原
KLH conjugated synthetic peptide: human C1s
抗原种属
Human
基因名称
C1S
基因ID
716
蛋白名称
Complement C1s subcomponent
Uniprot ID
P09871
功能
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
化学信息
分子量Theoretical: 47/75 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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