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Anti-ETHE1 Antibody (9J276) 是一种 Rabbit 抗体,靶向 ETHE1。Anti-ETHE1 Antibody (9J276) 可用于 ELISA。
Anti-ETHE1 Antibody (9J276) 是一种 Rabbit 抗体,靶向 ETHE1。Anti-ETHE1 Antibody (9J276) 可用于 ELISA。
产品描述 | Anti-ETHE1 Antibody (9J276) is a Rabbit antibody targeting ETHE1. Anti-ETHE1 Antibody (9J276) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9J276 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ETHE1 / HSCO (rh ETHE1 / HSCO; TMPY-03658; O95571; Leu13-Ala254). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic encephalopathy is an autosomal recessive, invariably fatal disorder characterized by early-onset encephalopathy, microangiopathy, chronic diarrhea, defective cytochrome c oxidase (COX) in muscle and brain, high concentrations of C4 and C5 acylcarnitines in blood and high excretion of ethylmalonic acid in urine. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ETHE1 / HSCO Protein (TMPY-03658) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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