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别名 YF13H12, HSCO, ethylmalonic encephalopathy 1
Anti-ETHE1 Antibody (9J276) 是一种 Rabbit 抗体,靶向 ETHE1。Anti-ETHE1 Antibody (9J276) 可用于 ELISA。
Anti-ETHE1 Antibody (9J276) 是一种 Rabbit 抗体,靶向 ETHE1。Anti-ETHE1 Antibody (9J276) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
| 产品描述 | Anti-ETHE1 Antibody (9J276) is a Rabbit antibody targeting ETHE1. Anti-ETHE1 Antibody (9J276) can be used in ELISA. |
| 别名 | YF13H12, HSCO, ethylmalonic encephalopathy 1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 9J276 |
| 交叉反应 | Human |
| 特异性 | Human ETHE1 |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ETHE1 / HSCO (rh ETHE1 / HSCO; TMPY-03658; O95571; Leu13-Ala254). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic encephalopathy is an autosomal recessive, invariably fatal disorder characterized by early-onset encephalopathy, microangiopathy, chronic diarrhea, defective cytochrome c oxidase (COX) in muscle and brain, high concentrations of C4 and C5 acylcarnitines in blood and high excretion of ethylmalonic acid in urine. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human ETHE1 / HSCO Protein (TMPY-03658) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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