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Anti-SAE1 Antibody (4G581)
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产品编号 TMAC-03680
别名 UBLE1A, SUMO1 activating enzyme subunit 1, SUA1, HSPC140, AOS1
Anti-SAE1 Antibody (4G581) 是一种 Rabbit 抗体，靶向 SAE1。Anti-SAE1 Antibody (4G581) 可用于 WB,FCM。
Anti-SAE1 Antibody (4G581)
Anti-SAE1 Antibody (4G581)
还可以产品编号 TMAC-03680 别名 UBLE1A, SUMO1 activating enzyme subunit 1, SUA1, HSPC140, AOS1
Anti-SAE1 Antibody (4G581) 是一种 Rabbit 抗体，靶向 SAE1。Anti-SAE1 Antibody (4G581) 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-SAE1 Antibody (4G581) is a Rabbit antibody targeting SAE1. Anti-SAE1 Antibody (4G581) can be used in WB,FCM. |
| 别名 | UBLE1A, SUMO1 activating enzyme subunit 1, SUA1, HSPC140, AOS1 |
| Ig Type | IgG |
| 克隆号 | 4G581 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of SAE1 on different cell lysates using anti-SAE1 antibody at 1/1,000 dilution. Positive control: Lane 1: SiHa, Lane 2: K562, Lane 3: 293. 2. Flow cytometric analysis of A549 cells with SAE1 antibody at 1/100 dilution (yellow) compared with an unlabelled control (cells without incubation with primary antibody; purple).Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteasome. AOS-1, also designated SUMO-1-activating enzyme or ubiquitin-like 1-activating enzyme E1A, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. AOS-1 can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: human SAE1 aa 150-300 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 38 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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