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Anti-CSF3R/G-CSFR Antibody (4H46)

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货号 TMAY-00480

别名 GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114

Anti-CSF3R/G-CSFR Antibody (4H46) 是一种 Mouse 抗体,靶向 CSF3R/G-CSFR。Anti-CSF3R/G-CSFR Antibody (4H46) 可用于 ELISA,ELISA(Det)。

Anti-CSF3R/G-CSFR Antibody (4H46)

Anti-CSF3R/G-CSFR Antibody (4H46)

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Rating icon 还可以
货号 TMAY-00480 别名 GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114

Anti-CSF3R/G-CSFR Antibody (4H46) 是一种 Mouse 抗体,靶向 CSF3R/G-CSFR。Anti-CSF3R/G-CSFR Antibody (4H46) 可用于 ELISA,ELISA(Det)。

规格价格库存数量
20 μL
¥ 580
5日内发货
100 μL
¥ 1,684
5日内发货
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产品介绍


生物活性
产品描述
Anti-CSF3R/G-CSFR Antibody (4H46) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4H46) can be used in ELISA,ELISA(Det).
别名GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Ig Type
Mouse IgG1
克隆号
4H46
反应种属
Human
特异性
Human CSF3R/G-CSFR
应用ELISAELISA(Det)
推荐剂量
ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSFR extracellular domain (rhG-CSFR; Catalog #10218-HCCH; Met1-Pro621; NP_000751.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Human cell-derived rhG-CSFR extracellular domain
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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