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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MAPK6 Polyclonal Antibody

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货号 TMAB-08590

Anti-MAPK6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MAPK6。Anti-MAPK6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MAPK6 Polyclonal Antibody

Anti-MAPK6 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08590

Anti-MAPK6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MAPK6。Anti-MAPK6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAPK6 Polyclonal Antibody is a Rabbit antibody targeting MAPK6. Anti-MAPK6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm (By similarity). Nucleus (By similarity). Note=Translocates to the cytoplasm following interaction with MAPKAPK5 (By similarity).
组织特异性Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein. Function : Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MAPK6/ERK3
抗原种属
Human
基因名称
MAPK6
基因ID
5597
蛋白名称
Mitogen-activated protein kinase 6
Uniprot ID
Q16659
功能
Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.
化学信息
分子量Theoretical: 83 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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