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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Alpha-synuclein Antibody (4T50)

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货号 TMAB-02493

Anti-Alpha-synuclein Antibody (4T50) 是一种 Rabbit 抗体，靶向 Alpha-synuclein。Anti-Alpha-synuclein Antibody (4T50) 可用于 WB。

Anti-Alpha-synuclein Antibody (4T50)

Anti-Alpha-synuclein Antibody (4T50)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02493

Anti-Alpha-synuclein Antibody (4T50) 是一种 Rabbit 抗体，靶向 Alpha-synuclein。Anti-Alpha-synuclein Antibody (4T50) 可用于 WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

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产品描述
Anti-Alpha-synuclein Antibody (4T50) is a Rabbit antibody targeting Alpha-synuclein. Anti-Alpha-synuclein Antibody (4T50) can be used in WB.
Ig Type
IgG
克隆号
4T50
反应种属
Rat,Mouse,Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons.
组织特异性Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].
抗原信息
免疫原
Recombinant Protein: human Alpha-synuclein
抗原种属
Human
基因名称
SNCA
基因ID
6622
蛋白名称
alpha-synuclein
Uniprot ID
P37840
功能
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
化学信息
分子量Theoretical: 14 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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