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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CYP26A1 Polyclonal Antibody

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货号 TMAB-04876

Anti-CYP26A1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP26A1。Anti-CYP26A1 Polyclonal Antibody 可用于 WB。

Anti-CYP26A1 Polyclonal Antibody

Anti-CYP26A1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04876

Anti-CYP26A1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP26A1。Anti-CYP26A1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CYP26A1 Polyclonal Antibody is a Rabbit antibody targeting CYP26A1. Anti-CYP26A1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane. Microsome membrane.
组织特异性Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor ∫2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CYP26A1
抗原种属
Human
基因名称
CYP26A1
基因ID
1592
蛋白名称
Cytochrome P450 26A1
Uniprot ID
O43174
功能
Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
化学信息
分子量Theoretical: 56 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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