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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IKB beta Antibody (8N845)

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货号 TMAB-07572

Anti-IKB beta Antibody (8N845) 是一种 Rabbit 抗体，靶向 IKB beta。Anti-IKB beta Antibody (8N845) 可用于 WB。

Anti-IKB beta Antibody (8N845)

Anti-IKB beta Antibody (8N845)

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Rating icon 还可以
货号 TMAB-07572

Anti-IKB beta Antibody (8N845) 是一种 Rabbit 抗体，靶向 IKB beta。Anti-IKB beta Antibody (8N845) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-IKB beta Antibody (8N845) is a Rabbit antibody targeting IKB beta. Anti-IKB beta Antibody (8N845) can be used in WB.
Ig Type
IgG
克隆号
8N845
反应种属
Human (predicted:Mouse)
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Expressed in all tissues examined.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
抗原信息
免疫原
KLH conjugated synthetic peptide: human IKB beta
抗原种属
Human
基因名称
NFKBIB
基因ID
4793
蛋白名称
NF-kappa-B inhibitor beta
Uniprot ID
Q15653
功能
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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