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Anti-BDNF Antibody (5C635)
还可以产品编号 TMAH-00113
别名 Brain-Derived Neurotrophic Factor, BDNF, Abrineurin
Anti-BDNF Antibody (5C635) 是一种抗体，靶向 BDNF。Anti-BDNF Antibody (5C635) 可用于 ELISA, WB。
Anti-BDNF Antibody (5C635)
Anti-BDNF Antibody (5C635)
还可以产品编号 TMAH-00113 别名 Brain-Derived Neurotrophic Factor, BDNF, Abrineurin
Anti-BDNF Antibody (5C635) 是一种抗体，靶向 BDNF。Anti-BDNF Antibody (5C635) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-BDNF Antibody (5C635) is an antibody targeting BDNF. Anti-BDNF Antibody (5C635) can be used in ELISA, WB. |
| 别名 | Brain-Derived Neurotrophic Factor, BDNF, Abrineurin |
| Ig Type | Rabbit IgG |
| 克隆号 | 5C635 |
| 交叉反应 | Human, Mouse |
| 验证活性 | Western Blot -Positive WB detected in: U87 whole cell lysate, U251 whole cell lysate, Mouse Brain tissue lysate -All lanes: BDNF antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 28 kDa -Observed band size: 28 kDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:500-1:2000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted.; [BDNF precursor form]: Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human BDNF |
| 抗原种属 | Human |
| 基因ID | 627 |
| Uniprot ID | |
| 研究领域 | Neuroscience, Cardiovascular, Metabolism |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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