Anti-HGFA Antibody (4U68)

Name: Anti-HGFA Antibody (4U68)
Brand: TargetMol
SKU: TMAY-00617
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00617

Anti-HGFA Antibody (4U68) 是一种 Mouse 抗体，靶向 HGFA。Anti-HGFA Antibody (4U68) 可用于 ELISA。

Anti-HGFA Antibody (4U68)

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产品编号 TMAY-00617

Anti-HGFA Antibody (4U68) 是一种 Mouse 抗体，靶向 HGFA。Anti-HGFA Antibody (4U68) 可用于 ELISA。

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产品描述	Anti-HGFA Antibody (4U68) is a Mouse antibody targeting HGFA. Anti-HGFA Antibody (4U68) can be used in ELISA.
Ig Type	Monoclonal Mouse IgG2a
克隆号	4U68
交叉反应	Human
应用	ELISA
推荐剂量	ELISA: 1:1000-1:2000
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HGFA (rhHGFA; TMPY-00821; NP_001519.1; Met 1-Ser 655). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is cleaved by thrombin or thermolysin through the endoproteolytic process and forms an active heterodimer linked by a disulfide bond. In turn, the active protease can be inhibited by HGFA inhibitors (HAIs) including HAI-1 and HAI-2. Besides, the HGFA zymogen acquires a strong affinity upon activation and thus may ensure the local action in tissue regeneration in the liver, kidney, and skin. It has been reported that activation of HGF is a critical limiting step in the HGF/SF-induced signaling pathway mediated by Met, and accordingly, aberrant expression of HGFA is implicated in tumorigenesis and progression.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human HGFA protein (TMPY-00821)
抗原种属	Human
研究领域	Serine Proteases and Regulators

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.