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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DUOXA2 Polyclonal Antibody

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货号 TMAB-05336

Anti-DUOXA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DUOXA2。Anti-DUOXA2 Polyclonal Antibody 可用于 WB。

Anti-DUOXA2 Polyclonal Antibody

Anti-DUOXA2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05336

Anti-DUOXA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DUOXA2。Anti-DUOXA2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-DUOXA2 Polyclonal Antibody is a Rabbit antibody targeting DUOXA2. Anti-DUOXA2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein.
组织特异性Specifically expressed in thyroid. Also detected in salivary glands. [PTM] N-glycosylated.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DUOXA2 is a 320 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the DUOXA family. Expressed specifically in thyroid and salivary glands, DUOXA2 is essential for the maturation and transport of DUOX2 from the ER to the plasma membrane and is also thought to play a role in the synthesis of thyroid hormone (TH). Defects in the DUOXA2 gene are associated with the pathogenesis of congenital hypothyroidism, a disorder that affects infants and is characterized by a significant decrease or a complete deficiency of TH from birth. The gene encoding DUOXA2 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DUOXA2
抗原种属
Human
基因名称
DUOXA2
基因ID
405753
蛋白名称
Dual oxidase maturation factor 2
Uniprot ID
Q1HG44
功能
Function: Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis.
化学信息
分子量Theoretical: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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