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Anti-Phospholipase C gamma 1 Antibody (7V238)
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产品编号 TMAC-03234
别名 PLC-II, PLC-gamma-1, PLCgamma1, PLCG1_HUMAN, Plcg1, PLC-148, PLC148, PLC1, PLC II, PLC gamma 1, Phospholipase C-II, Phospholipase C-gamma-1, Phospholipase C γ 1, Phospholipase C gamma 1, Phospholipase C g 1, Phospholipase C 148, Phosphoinositide phospholipase C-gamma-1, Phosphoinositide phospholipase C, Phosphoinositidase C, Phosphatidylinositol phospholipase C, NCKAP3, Monophosphatidylinositol phosphodiesterase, Inositoltrisphosphohydrolase, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1, 1 phosphatidyl D myo inositol 4 5 bisphosphate
Anti-Phospholipase C gamma 1 Antibody (7V238) 是一种 Rabbit 抗体，靶向 Phospholipase C gamma 1。Anti-Phospholipase C gamma 1 Antibody (7V238) 可用于 WB,ICC,IP。
Anti-Phospholipase C gamma 1 Antibody (7V238)
Anti-Phospholipase C gamma 1 Antibody (7V238)
还可以产品编号 TMAC-03234 别名 PLC-II, PLC-gamma-1, PLCgamma1, PLCG1_HUMAN, Plcg1, PLC-148, PLC148, PLC1, PLC II, PLC gamma 1, Phospholipase C-II, Phospholipase C-gamma-1, Phospholipase C γ 1, Phospholipase C gamma 1, Phospholipase C g 1, Phospholipase C 148, Phosphoinositide phospholipase C-gamma-1, Phosphoinositide phospholipase C, Phosphoinositidase C, Phosphatidylinositol phospholipase C, NCKAP3, Monophosphatidylinositol phosphodiesterase, Inositoltrisphosphohydrolase, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1, 1 phosphatidyl D myo inositol 4 5 bisphosphate
Anti-Phospholipase C gamma 1 Antibody (7V238) 是一种 Rabbit 抗体，靶向 Phospholipase C gamma 1。Anti-Phospholipase C gamma 1 Antibody (7V238) 可用于 WB,ICC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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| 产品描述 | Anti-Phospholipase C gamma 1 Antibody (7V238) is a Rabbit antibody targeting Phospholipase C gamma 1. Anti-Phospholipase C gamma 1 Antibody (7V238) can be used in WB,ICC,IP. |
| 别名 | PLC-II, PLC-gamma-1, PLCgamma1, PLCG1_HUMAN, Plcg1, PLC-148, PLC148, PLC1, PLC II, PLC gamma 1, Phospholipase C-II, Phospholipase C-gamma-1, Phospholipase C γ 1, Phospholipase C gamma 1, Phospholipase C g 1, Phospholipase C 148, Phosphoinositide phospholipase C-gamma-1, Phosphoinositide phospholipase C, Phosphoinositidase C, Phosphatidylinositol phospholipase C, NCKAP3, Monophosphatidylinositol phosphodiesterase, Inositoltrisphosphohydrolase, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1, 1 phosphatidyl D myo inositol 4 5 bisphosphate |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. ICC staining PLC γ1 in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. ICC staining PLC γ1 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; ICC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLC γ1, PLC γ2, PLC δ1, PLC δ2 and PLCε. PLC γ1 is widely distributed in bronchiolar epithelium, type I and II pneumocytes and fibroblasts of the interstitial tissue. Actin-regulatory protein Villin is tyrosine phosphorylated and associates with PLC γ1 in the brush border of intestinal epithelial cells. Villin regulates PLC γ1 activity by modifying its own ability to bind phosphatidylinositol 4,5-biphosphate. PLC γ1 binds Integrin α1/β1 and modulates Integrin α1/β-specific adhesion. PLC γ1 and Ca2+ play a direct role in VEGF-regulated endothelial growth, however this signaling pathway is not linked to FGF-mediated effects in primary endothelial cells. PLC γ1 is rapidly activated in response to growth factor stimulation and plays an important role in regulating cell proliferation and differentiation. It may also have a protective function during cellular response to oxidative stress. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 149 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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