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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LY6E Polyclonal Antibody

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货号 TMAB-08462

Anti-LY6E Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LY6E。Anti-LY6E Polyclonal Antibody 可用于 WB。

Anti-LY6E Polyclonal Antibody

Anti-LY6E Polyclonal Antibody

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货号 TMAB-08462

Anti-LY6E Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LY6E。Anti-LY6E Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-LY6E Polyclonal Antibody is a Rabbit antibody targeting LY6E. Anti-LY6E Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2. [provided by RefSeq, Aug 2021]
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse LY6E
抗原种属
Mouse
基因名称
Ly6e
基因ID
17069
蛋白名称
Lymphocyte antigen 6E
Uniprot ID
Q64253
功能
GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity).
Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion (PubMed:32641482).
Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity (By similarity).
化学信息
分子量Theoretical: 14 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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