购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部生物活性储存和溶解信息计算器

Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853)

Rating icon 还可以
Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853)
产品编号 TMAC-03231
别名 p-JAK2 (Y1007, 1008), p-JAK2 (Tyr1007, 1008), JAK2 (p-Y1007, 1008), JAK2 (p-Tyr1007, 1008)

Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) 是一种 Rabbit 抗体，靶向 Phospho-JAK2 (Y1007+Y1008)。Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) 可用于 WB,ICC,IHC,IP。

Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853)

Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853)

Rating icon 还可以
Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853)
产品编号 TMAC-03231 别名 p-JAK2 (Y1007, 1008), p-JAK2 (Tyr1007, 1008), JAK2 (p-Y1007, 1008), JAK2 (p-Tyr1007, 1008)

Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) 是一种 Rabbit 抗体，靶向 Phospho-JAK2 (Y1007+Y1008)。Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) 可用于 WB,ICC,IHC,IP。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853) 是一种 Rabbit 抗体，靶向 Phospho-JAK2 (Tyr1007, 1008)。Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853) 可用于 WB,ICC,IHC,IP。
别名p-JAK2 (Y1007, 1008), p-JAK2 (Tyr1007, 1008), JAK2 (p-Y1007, 1008), JAK2 (p-Tyr1007, 1008)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Phospho-JAK2 (Y1007+Y1008) antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-Phospho-JAK2 (Y1007+Y1008) antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Phospho-JAK2 (Y1007+Y1008) antibody. Counter stained with hematoxylin.
4. ICC staining Phospho-JAK2 (Y1007+Y1008) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Western blot analysis of JAK2 phosphorylation expression in Jurkat cell lysates treated with Pervanadate.
应用
WB
ICC
IHC
IP
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景JAK2 (Janus Kinase 2) belongs to the emerging family of non-receptor Janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immuno-logical stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK2. JAK2 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. The canonical JAK-Stat pathway is integral to maintaining a normal immune system by stimulating proliferation, differentiation, survival, and host resistance to pathogens. Altering JAK-Stat signaling to reduce cytokine induced pro-inflammatory responses represents an attractive target for inflammatory therapies. Within the JAK2 kinase domain, there is a region that has considerable sequence homology to the regulatory region of the insulin receptor. Among a variety of sites, Tyrosines 1007 and 1008 are sites of trans- or autophosphorylation in vivo and in in vitro kinase reactions.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human JAK2 around the phosphorylation site of Tyr1007 and 1008
抗原种属
human
Uniprot ID
O60674
化学信息
分子量Theoretical: 130 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

pJAK2 (Y1007, 1008)pJAK2 (Tyr1007, 1008)JAK2 (pY1007, 1008)JAK2 (pTyr1007, 1008)JAK2 (phospho-Y1007, 1008)JAK2 (phospho-Tyr1007, 1008)

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853) | purchase Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853) | Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853) cost | order Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853) | Anti-Phospho-JAK2 (Tyr1007, 1008) Antibody (1D853) molecular weight