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Anti-Cathepsin S Antibody (9S226)

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Anti-Cathepsin S Antibody (9S226)
产品编号 TMAY-03454
别名 Cats, cathepsin S, Cat S

Anti-Cathepsin S Antibody (9S226) 是一种 Rabbit 抗体，靶向 Cathepsin S。Anti-Cathepsin S Antibody (9S226) 可用于 ELISA。

Anti-Cathepsin S Antibody (9S226)
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Anti-Cathepsin S Antibody (9S226)

Rating icon 还可以
Anti-Cathepsin S Antibody (9S226)
产品编号 TMAY-03454 别名 Cats, cathepsin S, Cat S

Anti-Cathepsin S Antibody (9S226) 是一种 Rabbit 抗体，靶向 Cathepsin S。Anti-Cathepsin S Antibody (9S226) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,284
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产品介绍

生物活性
产品描述
Anti-Cathepsin S Antibody (9S226) is a Rabbit antibody targeting Cathepsin S. Anti-Cathepsin S Antibody (9S226) can be used in ELISA.
别名Cats, cathepsin S, Cat S
Ig Type
Rabbit IgG
克隆号
9S226
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Cathepsin S / CTSS (TMPY-02751; AAB94925.1; Met1-Ile340).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTSS is synthesized as inactive precursor of 331 amino acids consisting of a 15-aa signal peptide, a propeptide of 99 aa, and a mature polypeptide of 217 aa. It is activated in the lysosomes by a proteolytic cleavage of the propeptide. Cathepsin S is expressed in the lysosome of antigen presenting cells, primarily dendritic cells, B-cells and macrophages. Compared with other lysosomal cysteine proteases, cathepsin S has displayed some unique characteristics. Cathepsin S is most well known for its critical function in the proteolytic digestion of the invariant chain chaperone molecules, thus controlling antigen presentation to CD4+ T-cells by major histocompatibility complex (MHC) class II molecules or to NK1.1+ T-cells via CD1 molecules. Cathepsin S also appears to participate in direct processing of exogenous antigens for presentation by MHC class II to CD4+ T-cells, or in cross-presentation by MHC class I molecules to CD8+ T-cells. In addition, although direct evidence is still lacking, in its secreted form cathepsin S is implicated in degradation of the extracellular matrix, which may contribute to the pathology of a number of diseases, including arthritis, atherosclerosis, neurological diseases and chronic obstructive pulmonary disease.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse Cathepsin S / CTSS protein (TMPY-02751)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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