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顶部生物活性储存和溶解信息计算器

Anti-IL-6R Antibody-APC (6K916)

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产品编号 TMAY-00762A

别名 interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126

Anti-IL-6R Antibody-APC (6K916) 是一种 APC-conjugated Rabbit 抗体，靶向 IL-6R。Anti-IL-6R Antibody-APC (6K916) 可用于 FCM。

Anti-IL-6R Antibody-APC (6K916)

Anti-IL-6R Antibody-APC (6K916)

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Rating icon 还可以
产品编号 TMAY-00762A 别名 interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126

Anti-IL-6R Antibody-APC (6K916) 是一种 APC-conjugated Rabbit 抗体，靶向 IL-6R。Anti-IL-6R Antibody-APC (6K916) 可用于 FCM。

规格价格库存数量
25 T
¥ 1,090
5日内发货
100 T
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-6R Antibody-APC (6K916) is a APC-conjugated Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody-APC (6K916) can be used in FCM.
别名interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126
Ig Type
Rabbit IgG
克隆号
6K916
交叉反应
Human
特异性
Human IL-6R
验证活性
Flow cytometric analysis of Human IL-6R expression on U266 cells. Cells were stained with APC-conjugated anti-Human IL-6R. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-6R (rh IL-6R; TMPY-00864; NP_000556.1; Met1-Pro365), and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human IL-6R Protein (TMPY-00864)
抗原种属
Human
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

计算器

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关键词

CD-126CD 126

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